Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | polypeptide deformylase-like protein, putative | 0.0617 | 0.374 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.027 | 0.8748 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.2506 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.027 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0309 | 0.1182 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.1617 | 1 | 0.5 |
Onchocerca volvulus | 0.0498 | 0.2994 | 1 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0077 | 0.0296 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0063 | 0.027 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0077 | 0.2864 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0617 | 0.374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0309 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.027 | 0.1034 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0617 | 0.374 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0077 | 0.2864 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0437 | 0.2616 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0077 | 0.2864 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.0509 | 0.1946 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0077 | 0.2864 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.027 | 0.027 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.027 | 0.8748 |
Plasmodium falciparum | peptide deformylase | 0.1617 | 1 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0256 | 0.9466 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0077 | 0.0296 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.0509 | 0.1946 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.027 | 0.027 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0077 | 0.2864 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0509 | 0.1946 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0077 | 0.0296 |
Plasmodium vivax | peptide deformylase, putative | 0.1617 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0309 | 0.1182 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.027 | 0.8748 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.2506 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.027 | 0.8748 |
Mycobacterium ulcerans | peptide deformylase | 0.1617 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.2506 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0063 | 0.027 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0437 | 0.2616 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0077 | 0.0296 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.0509 | 0.1946 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0617 | 0.374 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0077 | 0.2864 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0617 | 0.374 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0617 | 0.374 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0617 | 0.374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.2506 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.027 | 0.1034 |
Trichomonas vaginalis | set domain proteins, putative | 0.0498 | 0.2994 | 1 |
Treponema pallidum | polypeptide deformylase (def) | 0.1617 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.1617 | 1 | 1 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.1617 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.1617 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.