Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0058 | 0 | 0.5 |
Onchocerca volvulus | 0.0369 | 1 | 0.5 | |
Schistosoma mansoni | tyrosinase precursor | 0.0369 | 1 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0091 | 0.1077 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0058 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0091 | 0.1077 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 0.1077 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 0.1077 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0369 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0058 | 0 | 0.5 |
Onchocerca volvulus | 0.0369 | 1 | 0.5 | |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0091 | 0.1077 | 1 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0091 | 0.1077 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0369 | 1 | 1 |
Onchocerca volvulus | 0.0369 | 1 | 0.5 | |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0369 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0369 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0369 | 1 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.0369 | 1 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0369 | 1 | 1 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0369 | 1 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0058 | 0 | 0.5 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0369 | 1 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0058 | 0 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0091 | 0.1077 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0058 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0091 | 0.1077 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0369 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0369 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0091 | 0.1077 | 1 |
Onchocerca volvulus | 0.0369 | 1 | 0.5 | |
Chlamydia trachomatis | methionine aminopeptidase | 0.0058 | 0 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0091 | 0.1077 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0091 | 0.1077 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0058 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.