Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1022 | 0.1022 |
Brugia malayi | TAR-binding protein | 0.0146 | 0.7096 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.1022 | 0.1022 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.1267 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0115 | 0.5373 | 0.7572 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.3359 | 0.3359 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.1267 | 0.1267 |
Echinococcus multilocularis | tar DNA binding protein | 0.0146 | 0.7096 | 0.7096 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.6506 | 0.9169 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7096 | 0.7096 |
Echinococcus multilocularis | geminin | 0.0198 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0036 | 0.1022 | 0.1022 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.1022 | 0.1022 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.1267 | 0.1267 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1022 | 0.1022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7096 | 0.7096 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0036 | 0.1022 | 0.144 |
Brugia malayi | RNA binding protein | 0.0146 | 0.7096 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.1022 | 0.1022 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0115 | 0.5373 | 0.7572 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.1267 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1022 | 0.1022 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.6506 | 0.9169 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0078 | 0.3359 | 0.4734 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0115 | 0.5373 | 0.7572 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.1022 | 0.1022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7096 | 0.7096 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7096 | 0.7096 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0146 | 0.7096 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1022 | 0.1022 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.3359 | 0.4734 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.1267 | 0.5 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0036 | 0.1022 | 0.144 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.5373 | 0.7572 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 1 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7096 | 0.7096 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.1267 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0146 | 0.7096 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0146 | 0.7096 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.6506 | 0.9169 |
Echinococcus granulosus | tar DNA binding protein | 0.0146 | 0.7096 | 0.7096 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.1267 | 0.1267 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0036 | 0.1022 | 0.144 |
Brugia malayi | hypothetical protein | 0.0041 | 0.1267 | 0.1786 |
Loa Loa (eye worm) | RNA binding protein | 0.0146 | 0.7096 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0036 | 0.1022 | 0.1022 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.1267 | 0.1267 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1022 | 0.144 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.