Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | choline:ethanolamine kinase | 0.0039 | 0.1564 | 0.1564 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.309 | 0.309 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.309 | 0.309 |
Echinococcus granulosus | acetylcholinesterase | 0.013 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0022 | 0 | 0.5 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus granulosus | choline:ethanolamine kinase | 0.0039 | 0.1564 | 0.1564 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Plasmodium falciparum | choline kinase | 0.0039 | 0.1564 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.013 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.309 | 0.309 |
Echinococcus multilocularis | acetylcholinesterase | 0.013 | 1 | 1 |
Loa Loa (eye worm) | choline/ethanolamine kinase | 0.0039 | 0.1564 | 0.1564 |
Echinococcus granulosus | acetylcholinesterase | 0.013 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.309 | 0.309 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.309 | 0.309 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0022 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.309 | 0.309 |
Echinococcus granulosus | carboxylesterase 5A | 0.013 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0022 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.309 | 0.309 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.309 | 0.309 |
Plasmodium vivax | choline kinase, putative | 0.0039 | 0.1564 | 0.5 |
Toxoplasma gondii | phosphotransferase enzyme family protein | 0.0039 | 0.1564 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.013 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.013 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 1 | 1 |
Brugia malayi | Choline/ethanolamine kinase family protein | 0.0039 | 0.1564 | 0.1564 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.013 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.309 | 0.309 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.