Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0131 | 0.1539 | 1 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0123 | 0.1349 | 0.1656 |
Entamoeba histolytica | protein kinase, putative | 0.0131 | 0.1539 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0131 | 0.1539 | 0.189 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.0384 | 0.8142 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0131 | 0.1539 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0131 | 0.1539 | 1 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0123 | 0.1349 | 0.1656 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0131 | 0.1539 | 0.1539 |
Trichomonas vaginalis | STE family protein kinase | 0.0123 | 0.1349 | 0.8711 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.1349 | 0.8764 |
Trichomonas vaginalis | STE family protein kinase | 0.0123 | 0.1349 | 0.8711 |
Trichomonas vaginalis | AGC family protein kinase | 0.0131 | 0.1539 | 1 |
Schistosoma mansoni | protein kinase | 0.0074 | 0.0064 | 0.0416 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0123 | 0.1349 | 0.1656 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0131 | 0.1539 | 1 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0131 | 0.1539 | 0.189 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1284 | 0.1284 |
Echinococcus granulosus | aurora kinase A | 0.0131 | 0.1539 | 0.189 |
Trichomonas vaginalis | AGC family protein kinase | 0.0131 | 0.1539 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.0131 | 0.1539 | 1 |
Schistosoma mansoni | protein kinase | 0.0131 | 0.1539 | 1 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0131 | 0.1539 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.0384 | 0.8142 | 1 |
Trypanosoma brucei | aurora B kinase | 0.0131 | 0.1539 | 0.5 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.0456 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0131 | 0.1539 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0131 | 0.1539 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0131 | 0.1539 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0123 | 0.1349 | 0.1656 |
Entamoeba histolytica | protein kinase, putative | 0.0074 | 0.0064 | 0.0416 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0131 | 0.1539 | 0.1539 |
Trichomonas vaginalis | AGC family protein kinase | 0.0131 | 0.1539 | 1 |
Leishmania major | protein kinase, putative | 0.0131 | 0.1539 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0123 | 0.1349 | 0.8711 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0131 | 0.1539 | 1 |
Brugia malayi | Protein kinase domain | 0.0123 | 0.1349 | 0.1349 |
Brugia malayi | serine/threonine kinase 12 | 0.0131 | 0.1539 | 0.1539 |
Entamoeba histolytica | protein kinase, putative | 0.0074 | 0.0064 | 0.0416 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0123 | 0.1349 | 0.1656 |
Entamoeba histolytica | protein kinase, putative | 0.0123 | 0.1349 | 0.8764 |
Entamoeba histolytica | p21-activated kinase | 0.0123 | 0.1349 | 0.8764 |
Loa Loa (eye worm) | AUR protein kinase | 0.0131 | 0.1539 | 0.1539 |
Entamoeba histolytica | protein kinase, putative | 0.0074 | 0.0064 | 0.0416 |
Loa Loa (eye worm) | AUR protein kinase | 0.0131 | 0.1539 | 0.1539 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0074 | 0.0064 | 0.0079 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0123 | 0.1349 | 0.1656 |
Giardia lamblia | Aurora kinase | 0.0131 | 0.1539 | 1 |
Toxoplasma gondii | aurora kinase | 0.0131 | 0.1539 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0123 | 0.1349 | 0.8711 |
Loa Loa (eye worm) | AUR protein kinase | 0.0131 | 0.1539 | 0.1539 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0121 | 0.1284 | 0.8276 |
Echinococcus multilocularis | aurora kinase A | 0.0131 | 0.1539 | 0.189 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0131 | 0.1539 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.1349 | 0.8764 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.