Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.3046 | 0.3046 |
Brugia malayi | Transient-receptor-potential like protein | 0.0264 | 0.3397 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0469 | 0.644 | 0.4609 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0541 | 0.7503 | 0.6218 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0469 | 0.644 | 0.4609 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0238 | 0.07 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1333 | 0.5 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0686 | 0.9649 | 0.9469 |
Loa Loa (eye worm) | hypothetical protein | 0.0445 | 0.609 | 0.609 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0686 | 0.9649 | 0.9469 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0541 | 0.7503 | 0.6218 |
Loa Loa (eye worm) | hypothetical protein | 0.0709 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0238 | 0.0238 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1333 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0709 | 1 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0469 | 0.644 | 0.4609 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0709 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1333 | 0.3923 |
Schistosoma mansoni | transient receptor potential channel | 0.0469 | 0.644 | 0.644 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1333 | 0.1333 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0469 | 0.644 | 0.4609 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3397 | 0.3397 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0709 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1333 | 0.1333 |
Schistosoma mansoni | transient receptor potential channel | 0.0469 | 0.644 | 0.644 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0238 | 0.07 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.