Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | DNA helicase recq5 | 0.0019 | 0.2517 | 0.4147 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.2517 | 0.5 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0096 | 0.5 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0019 | 0.2517 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.607 | 0.5371 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.1509 | 0.1427 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.2517 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0096 | 0.0381 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2517 | 0.5 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0019 | 0.2517 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1509 | 0.2486 |
Schistosoma mansoni | DNA helicase recq1 | 0.0019 | 0.2517 | 0.4147 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0096 | 0.0158 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0019 | 0.2517 | 0.2445 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0019 | 0.2517 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.1509 | 0.1427 |
Loa Loa (eye worm) | RecQ helicase | 0.0019 | 0.2517 | 0.2445 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0019 | 0.2517 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 1 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0019 | 0.2517 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2517 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 1 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.2517 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2517 | 0.1187 |
Echinococcus granulosus | bloom syndrome protein | 0.0019 | 0.2517 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.607 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0096 | 0.0000000020559 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1509 | 0.2486 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1509 | 0.2486 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0096 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0019 | 0.2517 | 0.1187 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0019 | 0.2517 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.2517 | 0.2445 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2517 | 0.1187 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0096 | 0.0381 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.2517 | 0.5 |
Echinococcus multilocularis | bloom syndrome protein | 0.0019 | 0.2517 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0019 | 0.2517 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2517 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.607 | 0.6032 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 1 | 1 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0019 | 0.2517 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.2517 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1509 | 0.2486 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.