Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.9966 | 0.5 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.4403 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.9966 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.0327 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.4403 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0003 | 0 | 0.5 |
Onchocerca volvulus | 0.0029 | 0.4403 | 0.5 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4688 | 0.4688 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.0327 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.4688 | 0.4334 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.9966 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4688 | 0.4688 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0003 | 0 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0651 | 0.0651 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.9966 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4403 | 0.4403 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.4688 | 0.4334 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.9966 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.9966 | 0.9966 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.