Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.5141 | 0.4714 |
Echinococcus granulosus | aspartyl aminopeptidase | 0.0076 | 0.3769 | 0.3222 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0808 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3769 | 0.7332 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0808 | 0.1571 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.5141 | 1 |
Plasmodium falciparum | M18 aspartyl aminopeptidase | 0.0076 | 0.3769 | 0.5 |
Onchocerca volvulus | 0.0028 | 0.0808 | 0.5 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0808 | 0.1571 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 1 | 1 |
Leishmania major | aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 | 0.0076 | 0.3769 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Echinococcus multilocularis | aspartyl aminopeptidase | 0.0076 | 0.3769 | 0.3222 |
Onchocerca volvulus | 0.0028 | 0.0808 | 0.5 | |
Echinococcus multilocularis | geminin | 0.0178 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0808 | 0.1571 |
Mycobacterium leprae | PROBABLE AMINOPEPTIDASE PEPC | 0.0076 | 0.3769 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.5141 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.5141 | 0.4714 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.5141 | 0.4714 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0076 | 0.3769 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0776 | 0.1509 |
Trypanosoma cruzi | aspartyl aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0076 | 0.3769 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.5141 | 0.4714 |
Entamoeba histolytica | aspartyl aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Trypanosoma brucei | aspartyl aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0076 | 0.3769 | 1 |
Trypanosoma brucei | aspartyl aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Schistosoma mansoni | aspartyl aminopeptidase (M18 family) | 0.0076 | 0.3769 | 0.3222 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.5141 | 0.4714 |
Mycobacterium tuberculosis | Probable aminopeptidase PepC | 0.0076 | 0.3769 | 0.5 |
Plasmodium vivax | M18 aspartyl aminopeptidase, putative | 0.0076 | 0.3769 | 0.5 |
Schistosoma mansoni | aspartyl aminopeptidase (M18 family) | 0.0076 | 0.3769 | 0.3222 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.5141 | 0.4714 |
Brugia malayi | Aspartyl aminopeptidase | 0.0076 | 0.3769 | 0.7332 |
Loa Loa (eye worm) | aspartyl aminopeptidase | 0.0076 | 0.3769 | 0.7332 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0808 | 0.1571 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3769 | 0.7332 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.5141 | 0.4714 |
Trypanosoma cruzi | metallo-peptidase, Clan MH, Family M20 | 0.0076 | 0.3769 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.