Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0279 | 0.6653 | 0.8694 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0156 | 0.2618 | 0.1428 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.4047 | 0.4047 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0301 | 0.7378 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.1825 | 0.1825 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1952 | 0.1952 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0301 | 0.7378 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.9848 | 0.9848 |
Schistosoma mansoni | protein kinase C mu | 0.0205 | 0.4242 | 0.409 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0141 | 0.2123 | 0.2123 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.6653 | 0.8634 |
Brugia malayi | Protein kinase c protein 2 | 0.0209 | 0.4346 | 0.589 |
Brugia malayi | protein kinase C II. | 0.0301 | 0.7378 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.014 | 0.2072 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.4325 | 0.4325 |
Echinococcus granulosus | protein kinase C gamma type | 0.0211 | 0.443 | 0.4692 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0205 | 0.4242 | 0.575 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0138 | 0.2019 | 0.2019 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0205 | 0.4242 | 0.4242 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Onchocerca volvulus | 0.0203 | 0.4174 | 0.3918 | |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0301 | 0.7378 | 0.7378 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.7625 | 0.7625 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0226 | 0.4925 | 0.5582 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.7625 | 0.7625 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0279 | 0.6653 | 0.8694 |
Onchocerca volvulus | 0.0208 | 0.4325 | 0.4184 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.6653 | 0.8634 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.4174 | 0.4174 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0161 | 0.2768 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.7625 | 0.7625 |
Brugia malayi | C1-like domain containing protein | 0.0205 | 0.4242 | 0.575 |
Echinococcus granulosus | protein kinase c iota type | 0.014 | 0.2072 | 0.0445 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Onchocerca volvulus | 0.0308 | 0.7625 | 1 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0301 | 0.7378 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0211 | 0.443 | 0.4692 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1952 | 0.1952 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0077 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.