Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0463 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.6327 | 0.8912 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.34 | 0.34 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0463 | 0.1247 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0463 | 0.1247 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0602 | 0.0848 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0463 | 0.0463 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.6327 | 0.8912 |
Echinococcus multilocularis | tumor protein p63 | 0.0328 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.3715 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0463 | 0.1247 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.1121 | 0.1579 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1021 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0463 | 0.0652 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0602 | 0.0848 |
Onchocerca volvulus | 0.0048 | 0.1021 | 0.0819 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0463 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1121 | 0.1579 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0237 | 0.7099 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.1121 | 0.1579 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0463 | 0.0463 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.3715 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0463 | 0.1247 |
Brugia malayi | follicle stimulating hormone receptor | 0.0237 | 0.7099 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.34 | 0.9153 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.7273 | 0.5 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.34 | 0.34 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.1021 | 0.2748 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0463 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0463 | 0.0652 |
Onchocerca volvulus | 0.0243 | 0.7273 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0602 | 0.1621 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0427 | 0.0427 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.3715 | 0.3715 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.1121 | 0.1579 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.