Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.6483 | 0.6483 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0257 | 1 | 1 |
Echinococcus granulosus | geminin | 0.018 | 0.6483 | 0.6483 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0146 | 0.4927 | 0.4927 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0064 | 0.0064 |
Brugia malayi | MH2 domain containing protein | 0.0127 | 0.4034 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.3056 | 0.3056 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2793 | 0.2793 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0127 | 0.4034 | 0.4034 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | geminin | 0.018 | 0.6483 | 0.6483 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.6483 | 0.6483 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0257 | 1 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0127 | 0.4034 | 0.4034 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0257 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.