Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0669 | 0.0669 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0474 | 0.7002 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0431 | 0.0431 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0431 | 0.0431 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.0669 | 0.0669 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.0669 | 0.0669 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0181 | 0.249 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0431 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1999 | 0.3112 |
Plasmodium vivax | peptide deformylase, putative | 0.0474 | 0.7002 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0437 | 0.6423 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0149 | 0.1999 | 0.3112 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0431 | 0.0431 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0102 | 0.1273 | 0.1982 |
Mycobacterium ulcerans | peptide deformylase | 0.0474 | 0.7002 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0431 | 0.0431 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0181 | 0.249 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0181 | 0.249 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.0669 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0669 | 0.1041 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0431 | 0.0431 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0063 | 0.0669 | 0.0669 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.0669 | 0.0955 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0669 | 1 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0063 | 0.0669 | 0.0669 |
Onchocerca volvulus | 0.0497 | 0.7351 | 1 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0149 | 0.1999 | 0.3112 |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0431 | 0.0431 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0669 | 0.0669 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.1273 | 0.1273 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0431 | 0.0431 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0181 | 0.249 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0431 | 0.0671 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0181 | 0.249 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0431 | 0.0431 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0669 | 0.0669 |
Plasmodium falciparum | peptide deformylase | 0.0474 | 0.7002 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0149 | 0.1999 | 0.3112 |
Chlamydia trachomatis | peptide deformylase | 0.0474 | 0.7002 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0431 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0431 | 0.0671 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0181 | 0.249 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.0669 | 0.0955 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0431 | 0.0431 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0474 | 0.7002 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.0474 | 0.7002 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0437 | 0.6423 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0181 | 0.249 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1273 | 0.1982 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0633 | 0.0633 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0431 | 0.0671 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0474 | 0.7002 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0669 | 1 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0497 | 0.7351 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0474 | 0.7002 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.