Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0115 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0006 | 0.0115 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0006 | 0.0115 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0006 | 0.0115 | 1 |
Schistosoma mansoni | brg-1 associated factor | 0.0006 | 0.0115 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0006 | 0.0115 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0006 | 0.0115 | 0.5 |
Onchocerca volvulus | 0.0006 | 0.0115 | 0.0115 | |
Schistosoma mansoni | hypothetical protein | 0.0006 | 0.0115 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0006 | 0.0115 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.3722 | 0.3722 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0006 | 0.0115 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0006 | 0.0115 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0006 | 0.0115 | 0.0115 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0006 | 0.0115 | 1 |
Treponema pallidum | hypothetical protein | 0.004 | 0.1642 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0006 | 0.0115 | 0.0115 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0006 | 0.0115 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0006 | 0.0115 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0224 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1642 | 1 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0139 | 0.6128 | 0.5 |
Leishmania major | ferric reductase, putative | 0.0139 | 0.6128 | 0.5 |
Onchocerca volvulus | Dual oxidase homolog | 0.0224 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0006 | 0.0115 | 0.5 |
Giardia lamblia | Programmed cell death protein-like protein | 0.0003 | 0 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0006 | 0.0115 | 0.0115 |
Trypanosoma brucei | ferric reductase transmembrane protein, putative | 0.0139 | 0.6128 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0006 | 0.0115 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0006 | 0.0115 | 0.0115 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0006 | 0.0115 | 0.5 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0139 | 0.6128 | 0.5 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0006 | 0.0115 | 0.0115 |
Chlamydia trachomatis | SWIB complex protein | 0.0006 | 0.0115 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0006 | 0.0115 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.