Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.7581 | 0.9346 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.808 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.808 | 0.7673 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.808 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.808 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.7581 | 0.9346 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.808 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.808 | 1 |
Brugia malayi | Inositol-1 | 0.0037 | 0.1748 | 0.1693 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.808 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.808 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.1748 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.7581 | 0.9346 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.808 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.808 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.808 | 0.7673 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0055 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.808 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.808 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.808 | 0.7673 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.1748 | 0.1693 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.1748 | 0.5 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.808 | 0.7673 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1748 | 0.1352 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.808 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.7581 | 0.9346 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.808 | 0.7988 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.808 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.1748 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.808 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0055 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.808 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1748 | 0.1352 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.808 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.