Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | pantothenate kinase 4 | 0.0088 | 1 | 1 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0088 | 1 | 1 |
Trypanosoma brucei | pantothenate kinase subunit, putative | 0.0088 | 1 | 1 |
Entamoeba histolytica | pantothenate kinase 1, putative | 0.0088 | 1 | 1 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0088 | 1 | 1 |
Plasmodium vivax | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Onchocerca volvulus | Fumble homolog | 0.0088 | 1 | 0.5 |
Giardia lamblia | Pantothenate kinase 4 | 0.0088 | 1 | 0.5 |
Loa Loa (eye worm) | pantothenate kinase | 0.0088 | 1 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Plasmodium falciparum | pantothenate kinase 1, putative | 0.0088 | 1 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0088 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0138 | 0.0138 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Toxoplasma gondii | pantothenate kinase | 0.0037 | 0.0909 | 0.0909 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0051 | 0.3352 | 0.3352 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Toxoplasma gondii | fumble protein | 0.0088 | 1 | 1 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0088 | 1 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0138 | 0.0138 |
Leishmania major | pantothenate kinase subunit, putative | 0.0088 | 1 | 1 |
Echinococcus granulosus | pantothenate kinase 4 | 0.0088 | 1 | 1 |
Schistosoma mansoni | pantothenate kinase | 0.0088 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.