Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Onchocerca volvulus | Fumble homolog | 0.0092 | 0.3061 | 0.3061 |
Entamoeba histolytica | pantothenate kinase 1, putative | 0.0092 | 0.3061 | 0.5 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Plasmodium falciparum | pantothenate kinase 1, putative | 0.0092 | 0.3061 | 0.5 |
Trypanosoma brucei | pantothenate kinase subunit, putative | 0.0092 | 0.3061 | 0.5 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Onchocerca volvulus | 0.014 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.014 | 1 | 1 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0092 | 0.3061 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5938 | 0.5938 |
Onchocerca volvulus | 0.014 | 1 | 1 | |
Echinococcus multilocularis | pantothenate kinase 4 | 0.0092 | 0.3061 | 1 |
Echinococcus granulosus | pantothenate kinase 4 | 0.0092 | 0.3061 | 1 |
Brugia malayi | pantothenate kinase family protein | 0.0092 | 0.3061 | 0.3061 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.0092 | 0.3061 | 0.5 |
Plasmodium vivax | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.014 | 1 | 1 |
Onchocerca volvulus | 0.014 | 1 | 1 | |
Schistosoma mansoni | pantothenate kinase | 0.0092 | 0.3061 | 0.3061 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 1 | 1 |
Giardia lamblia | Pantothenate kinase 4 | 0.0092 | 0.3061 | 0.5 |
Leishmania major | pantothenate kinase subunit, putative | 0.0092 | 0.3061 | 0.5 |
Schistosoma mansoni | pantothenate kinase | 0.0092 | 0.3061 | 0.3061 |
Loa Loa (eye worm) | pantothenate kinase | 0.0092 | 0.3061 | 0.3061 |
Trichomonas vaginalis | pantothenate kinase, putative | 0.0092 | 0.3061 | 0.5 |
Toxoplasma gondii | fumble protein | 0.0092 | 0.3061 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.