Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0092 | 0.1935 | 0.0048 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1935 | 0.1935 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1905 | 0.1905 |
Brugia malayi | hypothetical protein | 0.0234 | 0.8184 | 0.8184 |
Echinococcus multilocularis | maternal embryonic leucine zipper kinase | 0.0184 | 0.5998 | 0.6519 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1935 | 0.1935 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1935 | 0.1935 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0275 | 1 | 1 |
Brugia malayi | Kinase associated domain 1 family protein | 0.0091 | 0.1905 | 0.1905 |
Echinococcus granulosus | maternal embryonic leucine zipper kinase | 0.0184 | 0.5998 | 0.6502 |
Schistosoma mansoni | serine/threonine kinase | 0.0275 | 1 | 1 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0092 | 0.1935 | 0.0048 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.8184 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.8184 | 0.7757 |
Onchocerca volvulus | 0.0048 | 0 | 0.5 | |
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0092 | 0.1935 | 0.0048 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1935 | 0.1935 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1935 | 0.1935 |
Loa Loa (eye worm) | CAMK/CAMKL/MELK protein kinase | 0.0275 | 1 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.8184 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1905 | 0.1905 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.