Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0305 | 0.3777 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0305 | 0.3777 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.029 | 0.2096 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0056 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0056 | 0.0056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1352 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0056 | 0.0695 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0056 | 0.0056 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0202 | 0.2503 |
Mycobacterium leprae | Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0565 | 0.4142 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0056 | 0.0695 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0056 | 0.0056 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.029 | 0.2096 | 0.5 |
Mycobacterium tuberculosis | UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0565 | 0.4142 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0056 | 0.0695 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0389 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0808 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0389 | 0.0389 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0389 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0056 | 0.0056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.0808 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1352 | 1 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0202 | 0.0202 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.029 | 0.2096 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0797 | 0.5869 | 0.5869 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0202 | 0.0202 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0056 | 0.0056 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.0994 | 0.1612 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.019 | 0.2351 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.0808 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0056 | 0.0056 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.019 | 0.2351 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0202 | 0.0202 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0056 | 0.0695 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0389 | 0.0389 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0056 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0305 | 0.3777 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.029 | 0.2096 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0305 | 0.3777 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0056 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0202 | 0.0202 |
Mycobacterium ulcerans | UDP-galactopyranose mutase Glf | 0.0565 | 0.4142 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.029 | 0.2096 | 0.5 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.0994 | 0.1612 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0389 | 0.0389 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0389 | 0.0389 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.