Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0451 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3247 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.01 | 0.01 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.01 | 0.01 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3247 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0256 | 0.5194 | 0.5194 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0451 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0256 | 0.5194 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.01 | 0.01 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0256 | 0.5194 | 0.5194 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.01 | 0.01 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.