Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | amine GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0032 | 0.0153 | 0.0171 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.1452 | 1 | 0.5 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0032 | 0.0153 | 0.0171 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0312 | 0.2095 | 0.2207 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.1301 | 0.8952 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0032 | 0.0153 | 0.0171 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.1301 | 0.8952 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0515 | 0.0575 |
Loa Loa (eye worm) | hypothetical protein | 0.1452 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | neuropeptide receptor | 0.0032 | 0.0153 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0742 | 0.5077 | 0.5001 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0202 | 0.1332 | 0.5 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | opsin-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | neuropeptide receptor | 0.0032 | 0.0153 | 0.0171 |
Leishmania major | C-8 sterol isomerase-like protein | 0.1452 | 1 | 0.5 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.1452 | 1 | 0.5 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | opsin-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0032 | 0.0153 | 0.0171 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0202 | 0.1332 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0032 | 0.0153 | 0.0171 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.118 | 0.8108 | 0.9041 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0084 | 0.0515 | 0.0411 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0091 | 0.0562 | 0.0464 |
Schistosoma mansoni | thyroid hormone receptor | 0.0091 | 0.0562 | 0.0628 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | amine GPCR | 0.0032 | 0.0153 | 0.0171 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.1301 | 0.8952 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0084 | 0.0515 | 0.0411 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | myosin xvIII | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | thyroid hormone receptor | 0.0091 | 0.0562 | 0.0628 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | amine GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | histamine h1 receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | amine GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0032 | 0.0153 | 0.0171 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.118 | 0.8108 | 0.9041 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0032 | 0.0153 | 0.0171 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.1301 | 0.8952 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | neuropeptide receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | amine GPCR | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0032 | 0.0153 | 0.0171 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.1301 | 0.8952 | 0.8936 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0032 | 0.0153 | 0.0171 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0032 | 0.0153 | 0.0171 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.1301 | 0.8952 | 0.8936 |
Schistosoma mansoni | neuropeptide receptor | 0.0032 | 0.0153 | 0.0171 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.