Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1789 | 0.1293 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0054 | 0.057 | 0.039 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0077 | 0.1789 | 1 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0055 | 0.0625 | 0.0059 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0077 | 0.1789 | 0.1789 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6506 | 1 |
Brugia malayi | WGR domain containing protein | 0.0077 | 0.1789 | 0.1632 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0146 | 0.5458 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0054 | 0.057 | 0.0606 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6506 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.057 | 0.0606 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0054 | 0.057 | 0.039 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0067 | 0.1233 | 0.1656 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Echinococcus granulosus | carbonic anhydrase II | 0.0054 | 0.057 | 0.057 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0077 | 0.1789 | 0.2535 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.014 | 0.5165 | 0.5 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Brugia malayi | WGR domain containing protein | 0.014 | 0.5165 | 0.5073 |
Onchocerca volvulus | 0.0047 | 0.0187 | 0.5 | |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0077 | 0.1789 | 1 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.014 | 0.5165 | 0.5165 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Echinococcus granulosus | geminin | 0.0165 | 0.6506 | 0.6506 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Schistosoma mansoni | carbonic anhydrase | 0.0054 | 0.057 | 0.0606 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.014 | 0.5165 | 0.4873 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0054 | 0.057 | 0.0606 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Plasmodium falciparum | carbonic anhydrase | 0.0054 | 0.057 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0054 | 0.057 | 0.039 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0077 | 0.1789 | 0.1293 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0165 | 0.6506 | 0.6295 |
Leishmania major | carbonic anhydrase-like protein | 0.0054 | 0.057 | 0.5 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.014 | 0.5165 | 0.7877 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3376 | 0.2975 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0077 | 0.1789 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.