Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.3595 | 0.3595 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.7744 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.7744 | 0.7397 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.7744 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.7744 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 1 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.3595 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.3595 | 0.3595 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.3595 | 0.3595 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.7744 | 1 |
Onchocerca volvulus | 0.0026 | 1 | 1 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.7744 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.9658 | 0.9658 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.7744 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.7744 | 0.7744 |
Echinococcus multilocularis | musashi | 0.0026 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.7744 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 0.5 |
Echinococcus granulosus | lamin | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.3595 | 0.3595 |
Echinococcus multilocularis | lamin | 0.0026 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.7744 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.7744 | 0.7397 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 1 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.7744 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.7744 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.7744 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.7744 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.3595 | 0.3595 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.3595 | 0.139 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.7744 | 0.7397 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.1333 | 0.1333 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.3595 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.7744 | 0.7744 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.7744 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 1 | 1 |
Onchocerca volvulus | 0.0026 | 1 | 1 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.7744 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.3595 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.7744 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0342 | 0.0342 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.7744 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.7744 | 0.7744 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.7744 | 0.5 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.7744 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.