Detailed information for compound 805210

Basic information

Technical information
  • TDR Targets ID: 805210
  • Name: ZERO/005133
  • MW: 211.258 | Formula: C11H17NO3
  • H donors: 2 H acceptors: 2 LogP: -0.88 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCc1c(CC(C)C)oc(c1C(=O)O)C
  • InChi: 1S/C11H17NO3/c1-6(2)4-9-8(5-12)10(11(13)14)7(3)15-9/h6H,4-5,12H2,1-3H3,(H,13,14)
  • InChiKey: UDHBELQCCIULDQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • BAS 07207370
  • ZINC02586580

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni frizzled-like receptor 0.0064 0.1226 0.276
Schistosoma mansoni biogenic amine receptor 0.0137 0.3011 0.7095
Echinococcus granulosus tm gpcr rhodopsin 0.0137 0.3011 0.7121
Loa Loa (eye worm) sfrp2 0.0064 0.1226 0.1226
Schistosoma mansoni amine GPCR 0.0137 0.3011 0.7095
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0137 0.3011 0.7121
Schistosoma mansoni growth hormone secretagogue receptor 0.0137 0.3011 0.7095
Brugia malayi larval opioid receptor 0.0137 0.3011 0.7121
Echinococcus granulosus neuropeptide Y receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis neuropeptide s receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus frizzled 0.0064 0.1226 0.2824
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0064 0.1226 0.1226
Echinococcus multilocularis orexin receptor type 2 0.0137 0.3011 0.7121
Echinococcus multilocularis wnt family member wnt11 2 0.0124 0.2691 0.635
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi Unc-6 protein precursor 0.0186 0.4207 1
Echinococcus multilocularis protein Wnt 1 0.0124 0.2691 0.635
Echinococcus granulosus frizzled 0.0064 0.1226 0.2824
Echinococcus multilocularis g protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis neuropeptides capa receptor 0.0137 0.3011 0.7121
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0137 0.3011 0.7121
Brugia malayi wnt family protein 0.0124 0.2691 0.635
Schistosoma mansoni alpha-1 adrenergic receptor 0.0137 0.3011 0.7095
Echinococcus multilocularis frizzled 10 0.0064 0.1226 0.2824
Brugia malayi wnt family protein 0.0124 0.2691 0.635
Echinococcus granulosus alpha 1A adrenergic receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis somatostatin receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0137 0.3011 0.7095
Schistosoma mansoni wnt related 0.0124 0.2691 0.6318
Echinococcus granulosus dro:myosuppressin receptor 0.0137 0.3011 0.7121
Echinococcus granulosus frizzled 5 0.0064 0.1226 0.2824
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0137 0.3011 0.7121
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0137 0.3011 0.7121
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0064 0.1226 0.2824
Schistosoma mansoni hypothetical protein 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis neuropeptide receptor 0.0137 0.3011 0.7121
Echinococcus granulosus protein Wnt 2 0.0124 0.2691 0.635
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0137 0.3011 0.7121
Schistosoma mansoni neuropeptide f receptor 76f 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus neuropeptide receptor A26 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus netrin 1 0.0186 0.4207 1
Schistosoma mansoni neuropeptide F-like receptor 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus fmrfamide receptor 0.0137 0.3011 0.7121
Echinococcus granulosus G protein coupled receptor 139 0.0137 0.3011 0.7121
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0137 0.3011 0.3011
Echinococcus granulosus biogenic amine 5HT receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis neuropeptide receptor A26 0.0137 0.3011 0.7121
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0137 0.3011 0.7121
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0137 0.3011 0.7095
Echinococcus multilocularis G protein coupled receptor 139 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus Protein Wnt-5 0.0124 0.2691 0.635
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0026 0.5
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0137 0.3011 0.7121
Brugia malayi Dopamine receptor protein 1 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis secreted frizzled protein 0.0064 0.1226 0.2824
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0026 0.5
Brugia malayi G protein-coupled receptor F59B2.13 0.0137 0.3011 0.7121
Schistosoma mansoni netrin 0.0186 0.4207 1
Echinococcus granulosus secreted frizzled protein 0.0064 0.1226 0.2824
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis frizzled 5 0.0064 0.1226 0.2824
Echinococcus granulosus tm gpcr rhodopsin 0.0137 0.3011 0.7121
Brugia malayi Dopamine receptor protein 2 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0064 0.1226 0.1226
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus multilocularis neuropeptide FF receptor 2 0.0137 0.3011 0.7121
Schistosoma mansoni biogenic amine (5HT) receptor 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0064 0.1226 0.1226
Echinococcus granulosus 7TM GPCR rhodopsin 0.0137 0.3011 0.7121
Echinococcus granulosus Protein Wnt-11b 0.0124 0.2691 0.635
Echinococcus multilocularis secreted frizzled protein 5 0.0064 0.1226 0.2824
Echinococcus granulosus secreted frizzled protein 5 0.0064 0.1226 0.2824
Brugia malayi Serotonin receptor 0.0137 0.3011 0.7121
Brugia malayi G-protein coupled receptor 0.0137 0.3011 0.7121
Brugia malayi Fz domain containing protein 0.0064 0.1226 0.2824
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus neuropeptide s receptor 0.0137 0.3011 0.7121
Schistosoma mansoni neuropeptide receptor 0.0137 0.3011 0.7095
Echinococcus granulosus neuropeptide receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0137 0.3011 0.3011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi Dopamine receptor 0.0137 0.3011 0.7121
Brugia malayi follicle stimulating hormone receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) melatonin receptor type 1A 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis neuropeptide Y receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0124 0.2691 0.2691
Loa Loa (eye worm) G-protein coupled receptor 0.0137 0.3011 0.3011
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0137 0.3011 0.7121
Schistosoma mansoni neuropeptide receptor 0.0137 0.3011 0.7095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus g-protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis g-protein coupled receptor 0.0137 0.3011 0.7121
Schistosoma mansoni amine GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Schistosoma mansoni neuropeptide receptor 0.0137 0.3011 0.7095
Schistosoma mansoni wnt inhibitor frzb2 0.0064 0.1226 0.276
Echinococcus multilocularis fmrfamide receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis neuropeptide Y receptor 0.0137 0.3011 0.7121
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0137 0.3011 0.7121
Brugia malayi wnt family protein 0.0124 0.2691 0.635
Loa Loa (eye worm) G-protein coupled receptor 0.0137 0.3011 0.3011
Schistosoma mansoni wnt-5 0.0124 0.2691 0.6318
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni wnt related 0.0124 0.2691 0.6318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus somatostatin receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0124 0.2691 0.2691
Brugia malayi ORL1-like opioid receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0137 0.3011 0.3011
Schistosoma mansoni neuropeptide receptor 0.0137 0.3011 0.7095
Schistosoma mansoni opsin-like receptor 0.0137 0.3011 0.7095
Echinococcus granulosus neuropeptide receptor 0.0137 0.3011 0.7121
Echinococcus granulosus g protein coupled receptor 0.0137 0.3011 0.7121
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus orexin receptor type 2 0.0137 0.3011 0.7121
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0186 0.4207 0.4207
Brugia malayi G protein-coupled receptor 0.0137 0.3011 0.7121
Schistosoma mansoni frizzled-like receptor 0.0064 0.1226 0.276
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0422 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0137 0.3011 0.7095
Echinococcus multilocularis frizzled 4 0.0064 0.1226 0.2824
Schistosoma mansoni biogenic amine receptor 0.0137 0.3011 0.7095
Echinococcus multilocularis neuropeptide receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) wnt-4 protein 0.0124 0.2691 0.2691
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis frizzled 0.0064 0.1226 0.2824
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0137 0.3011 0.7095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus serotonin receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0137 0.3011 0.3011
Brugia malayi Wnt-4 protein precursor 0.0124 0.2691 0.635
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus g protein coupled receptor 0.0137 0.3011 0.7121
Schistosoma mansoni hypothetical protein 0.0137 0.3011 0.7095
Echinococcus multilocularis frizzled 0.0064 0.1226 0.2824
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0137 0.3011 0.7121
Echinococcus granulosus smoothened 0.0064 0.1226 0.2824
Loa Loa (eye worm) hypothetical protein 0.0124 0.2691 0.2691
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0137 0.3011 0.7121
Echinococcus granulosus protein Wnt 1 0.0124 0.2691 0.635
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Brugia malayi neuropeptide F receptor 0.0137 0.3011 0.7121
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0137 0.3011 0.7095
Echinococcus granulosus frizzled 4 0.0064 0.1226 0.2824
Echinococcus granulosus Protein Wnt-111 0.0124 0.2691 0.635
Schistosoma mansoni secreted frizzled-related protein 0.0064 0.1226 0.276
Echinococcus multilocularis WNT 0.0124 0.2691 0.635
Echinococcus multilocularis fmrfamide receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis dro:myosuppressin receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Schistosoma mansoni biogenic amine receptor 0.0137 0.3011 0.7095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0137 0.3011 0.7095
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0137 0.3011 0.7121
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0137 0.3011 0.7095
Echinococcus multilocularis secreted frizzled protein 0.0064 0.1226 0.2824
Echinococcus granulosus allatostatin A receptor 0.0137 0.3011 0.7121
Brugia malayi sulfakinin receptor protein 0.0137 0.3011 0.7121
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0064 0.1226 0.1226
Schistosoma mansoni opsin-like receptor 0.0137 0.3011 0.7095
Loa Loa (eye worm) neuropeptide F receptor 0.0137 0.3011 0.3011
Echinococcus multilocularis wingless type MMTV integration site family 0.0124 0.2691 0.635
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0137 0.3011 0.7095
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0124 0.2691 0.2691
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0137 0.3011 0.7121
Schistosoma mansoni wnt related 0.0124 0.2691 0.6318
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0137 0.3011 0.3011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0124 0.2691 0.2691
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0137 0.3011 0.7121
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0137 0.3011 0.7121
Echinococcus granulosus g protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis g protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni histamine h1 receptor 0.0137 0.3011 0.7095
Brugia malayi wnt family protein 0.0124 0.2691 0.635
Loa Loa (eye worm) CWN-2 protein 0.0124 0.2691 0.2691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Schistosoma mansoni frizzled 0.0064 0.1226 0.276
Echinococcus multilocularis smoothened 0.0064 0.1226 0.2824
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0016 0.0052 0.0052
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis netrin 1 0.0186 0.4207 1
Schistosoma mansoni neuropeptide F-like receptor 0.0137 0.3011 0.7095
Schistosoma mansoni adenoreceptor 0.0137 0.3011 0.7095
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Loa Loa (eye worm) Wnt2 protein 0.0124 0.2691 0.2691
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0137 0.3011 0.7095
Echinococcus granulosus biogenic amine 5HT receptor 0.0137 0.3011 0.7121
Brugia malayi neuropeptide F receptor 0.0137 0.3011 0.7121
Brugia malayi AKH receptor 0.0137 0.3011 0.7121
Brugia malayi Fz domain containing protein 0.0064 0.1226 0.2824
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0137 0.3011 0.7121
Schistosoma mansoni opsin-like receptor 0.0137 0.3011 0.7095
Brugia malayi Wnt-2 protein precursor 0.0124 0.2691 0.635
Schistosoma mansoni wnt related 0.0124 0.2691 0.6318
Echinococcus multilocularis neuropeptides capa receptor 0.0137 0.3011 0.7121
Brugia malayi Serotonin receptor 0.0137 0.3011 0.7121
Schistosoma mansoni hypothetical protein 0.0137 0.3011 0.7095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Schistosoma mansoni amine GPCR 0.0137 0.3011 0.7095
Loa Loa (eye worm) TYRA-2 protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) neuropeptide F receptor 0.0137 0.3011 0.3011
Brugia malayi RE15519p 0.0137 0.3011 0.7121
Brugia malayi putative neuropeptide receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus tm gpcr rhodopsin 0.0137 0.3011 0.7121
Echinococcus granulosus 7tm_1 domain containing protein 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0137 0.3011 0.7121
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0137 0.3011 0.7095
Echinococcus granulosus neuropeptide FF receptor 2 0.0137 0.3011 0.7121
Echinococcus multilocularis allatostatin A receptor 0.0137 0.3011 0.7121
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0064 0.1226 0.2824
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi G-protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus granulosus hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus Protein Wnt-04 0.0124 0.2691 0.635
Echinococcus multilocularis WNT 0.0124 0.2691 0.635
Echinococcus granulosus tachykinin peptides receptor 99D 0.0137 0.3011 0.7121
Brugia malayi putative neuropeptide receptor NPR1 0.0137 0.3011 0.7121
Brugia malayi GnHR receptor homolog 0.0137 0.3011 0.7121
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni hypothetical protein 0.0137 0.3011 0.7095
Echinococcus granulosus neuropeptide Y receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis g protein coupled receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Brugia malayi Tachykinin-like peptides receptor 99D 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus multilocularis serotonin receptor 0.0137 0.3011 0.7121
Echinococcus multilocularis serotonin receptor 0.0137 0.3011 0.7121
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0137 0.3011 0.7095
Echinococcus granulosus rhodopsin orphan GPCR 0.0137 0.3011 0.7121
Schistosoma mansoni amine GPCR 0.0137 0.3011 0.7095
Schistosoma mansoni myosin xvIII 0.0137 0.3011 0.7095
Echinococcus multilocularis sex peptide receptor 0.0137 0.3011 0.7121
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Echinococcus granulosus peptide allatostatin:somatostatin 0.0137 0.3011 0.7121
Schistosoma mansoni amine GPCR 0.0137 0.3011 0.7095
Schistosoma mansoni netrin 0.0186 0.4207 1
Brugia malayi Melatonin receptor type 1A 0.0137 0.3011 0.7121
Echinococcus multilocularis protein Wnt 2 0.0124 0.2691 0.635
Echinococcus granulosus sex peptide receptor 0.0137 0.3011 0.7121
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0137 0.3011 0.7095
Echinococcus granulosus frizzled 0.0064 0.1226 0.2824
Loa Loa (eye worm) hypothetical protein 0.0137 0.3011 0.3011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0137 0.3011 0.7095
Onchocerca volvulus 0.025 0.5777 1
Brugia malayi hypothetical protein 0.0137 0.3011 0.7121
Echinococcus granulosus neuropeptides capa receptor 0.0137 0.3011 0.7121
Echinococcus granulosus neuropeptides capa receptor 0.0137 0.3011 0.7121
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0137 0.3011 0.7095

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.