Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin b | 0.0756 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0084 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0756 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0756 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0756 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Plasmodium vivax | vivapain-1 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0264 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0264 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0756 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0756 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0264 | 0.2688 | 0.2688 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0756 | 1 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0264 | 0.2688 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Plasmodium vivax | unspecified product | 0.0084 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0084 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0084 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0264 | 0.2688 | 0.2688 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0264 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0264 | 0.2688 | 0.2688 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0084 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.