Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0446 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Plasmodium vivax | unspecified product | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0446 | 1 | 1 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0156 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase 2 | 0.0049 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0156 | 0.2688 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0049 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0156 | 0.2688 | 0.2688 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0156 | 0.2688 | 0.2688 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0049 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0156 | 0.2688 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0049 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0049 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0156 | 0.2688 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0446 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0156 | 0.2688 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0156 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Plasmodium vivax | vivapain-1 | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Echinococcus granulosus | cathepsin b | 0.0446 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0446 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0446 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0446 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0446 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0446 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0446 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0156 | 0.2688 | 0.2688 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Onchocerca volvulus | 0.0049 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0049 | 0 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0156 | 0.2688 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0049 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.