Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0218 | 0.5643 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0178 | 0.2278 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.015 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0187 | 0.3072 | 0.1027 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0218 | 0.5643 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.015 | 0 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.015 | 0 | 0.5 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0218 | 0.5643 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0218 | 0.5643 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.015 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0187 | 0.3072 | 0.1027 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0218 | 0.5643 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0271 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0271 | 1 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0218 | 0.5643 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.