Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0112 | 0.0161 | 0.0161 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0208 | 0.1102 | 0.1102 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0112 | 0.0161 | 0.0161 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0112 | 0.0161 | 0.0161 |
Echinococcus multilocularis | protein kinase c iota type | 0.0191 | 0.094 | 0.094 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0112 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0112 | 0.0161 | 0.0161 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0112 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0161 | 0.0161 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0112 | 0.0161 | 0.0161 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0112 | 0.0161 | 0.0161 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0907 | 0.798 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.1112 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0112 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0112 | 0.0161 | 0.0138 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0907 | 0.798 | 0.798 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0112 | 0.0161 | 0.0161 |
Brugia malayi | Protein kinase domain containing protein | 0.0112 | 0.0161 | 0.0138 |
Echinococcus granulosus | protein kinase c iota type | 0.0191 | 0.094 | 0.094 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0112 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0112 | 0.0161 | 0.0161 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0112 | 0.0161 | 0.5 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0208 | 0.1102 | 0.1102 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0112 | 0.0161 | 0.0138 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0129 | 0.0323 | 0.0323 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0112 | 0.0161 | 0.0161 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0112 | 0.0161 | 0.0161 |
Toxoplasma gondii | AGC kinase | 0.0112 | 0.0161 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.1016 | 0.9059 | 0.9059 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1112 | 1 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0191 | 0.094 | 0.094 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0208 | 0.1102 | 0.1102 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0112 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0112 | 0.0161 | 0.0161 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.1112 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0112 | 0.0161 | 0.0161 |
Schistosoma mansoni | serine/threonine kinase | 0.0112 | 0.0161 | 0.0161 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0129 | 0.0323 | 0.0323 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.1112 | 1 | 1 |
Onchocerca volvulus | 0.0096 | 0 | 0.5 | |
Brugia malayi | Protein kinase domain containing protein | 0.0112 | 0.0161 | 0.0138 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0112 | 0.0161 | 0.0161 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0208 | 0.1102 | 0.1102 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0112 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0112 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0112 | 0.0161 | 0.0161 |
Brugia malayi | Protein kinase domain containing protein | 0.0112 | 0.0161 | 0.0138 |
Trichomonas vaginalis | AGC family protein kinase | 0.0112 | 0.0161 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.