Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Echinococcus granulosus | nephrin | 0.0018 | 0.5533 | 1 |
Echinococcus granulosus | Immunoglobulin | 0.0018 | 0.5533 | 1 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.5533 | 1 |
Echinococcus multilocularis | nephrin | 0.0018 | 0.5533 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.5674 | 0.5674 |
Toxoplasma gondii | rhoptry neck protein RON1 | 0.0012 | 0 | 0.5 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0023 | 1 | 1 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0023 | 1 | 1 |
Toxoplasma gondii | rhoptry neck protein RON9 | 0.0012 | 0 | 0.5 |
Echinococcus granulosus | nephrin | 0.0018 | 0.5533 | 1 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Echinococcus granulosus | irregular chiasm roughest protein | 0.0018 | 0.5533 | 1 |
Brugia malayi | hypothetical protein | 0.0023 | 1 | 1 |
Echinococcus multilocularis | Immunoglobulin | 0.0018 | 0.5533 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.5533 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0023 | 1 | 1 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0018 | 0.5533 | 1 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Plasmodium falciparum | apical sushi protein | 0.0012 | 0 | 0.5 |
Echinococcus multilocularis | irregular chiasm roughest protein immunoglobulin set domain containing protein | 0.0018 | 0.5533 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1176 | 0.1176 |
Plasmodium vivax | apical sushi protein, putative | 0.0012 | 0 | 0.5 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Brugia malayi | GCC2 and GCC3 family protein | 0.0018 | 0.5674 | 0.5674 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.