Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hexokinase, putative | 0.4563 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.4563 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.4563 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.4563 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.4563 | 1 | 0.5 |
Schistosoma mansoni | hexokinase | 0.4563 | 1 | 0.5 |
Onchocerca volvulus | 0.4563 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1451 | 0.0123 | 0.0123 |
Brugia malayi | Hexokinase family protein | 0.2863 | 0.4604 | 0.4604 |
Trypanosoma cruzi | hexokinase, putative | 0.4563 | 1 | 0.5 |
Onchocerca volvulus | 0.4563 | 1 | 1 | |
Plasmodium falciparum | hexokinase | 0.4563 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.4563 | 1 | 1 |
Onchocerca volvulus | 0.4563 | 1 | 1 | |
Echinococcus granulosus | hexokinase type 2 | 0.4563 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.4563 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.4563 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3112 | 0.5396 | 0.5396 |
Treponema pallidum | hexokinase (hxk) | 0.4563 | 1 | 0.5 |
Toxoplasma gondii | hexokinase | 0.4563 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.4563 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.2863 | 0.4604 | 0.4604 |
Plasmodium vivax | hexokinase, putative | 0.4563 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.1451 | 0.0123 | 0.0123 |
Trypanosoma cruzi | hexokinase, putative | 0.4563 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.4563 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.4563 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1451 | 0.0123 | 0.0123 |
Entamoeba histolytica | hexokinase 2 | 0.4563 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.4563 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.4563 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.4563 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.4563 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.4563 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase type II | 0.4563 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.