Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trypanosoma brucei | cytosolic malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Trypanosoma brucei | mitochondrial malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Leishmania major | malate dehydrogenase, putative | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Toxoplasma gondii | lactate dehydrogenase LDH1 | 0.0186 | 1 | 0.5 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0186 | 1 | 1 |
Toxoplasma gondii | malate dehydrogenase MDH | 0.0186 | 1 | 0.5 |
Trypanosoma brucei | malate dehydrogenase-related | 0.0072 | 0.2592 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | malate dehydrogenase | 0.0186 | 1 | 0.5 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Mycobacterium leprae | PROBABLE MALATE DEHYDROGENASE MDH | 0.0072 | 0.2592 | 0.5 |
Echinococcus multilocularis | L lactate dehydrogenase B chain | 0.0186 | 1 | 1 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Plasmodium falciparum | L-lactate dehydrogenase | 0.0186 | 1 | 1 |
Echinococcus multilocularis | lactate dehydrogenase protein | 0.0186 | 1 | 1 |
Chlamydia trachomatis | malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Echinococcus granulosus | L lactate dehydrogenase | 0.0114 | 0.5289 | 0.3641 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0072 | 0.2592 | 0.2592 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Echinococcus granulosus | lactate dehydrogenase protein | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0072 | 0.2592 | 0.2592 |
Giardia lamblia | Malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Plasmodium vivax | lactate dehydrogenase | 0.0186 | 1 | 1 |
Trypanosoma brucei | glycosomal malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Plasmodium falciparum | malate dehydrogenase | 0.0186 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 1 | 1 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Brugia malayi | Malate dehydrogenase, cytoplasmic | 0.0072 | 0.2592 | 0.2592 |
Mycobacterium tuberculosis | Probable malate dehydrogenase Mdh | 0.0072 | 0.2592 | 0.5 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Echinococcus granulosus | L lactate dehydrogenase B chain | 0.0186 | 1 | 1 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0186 | 1 | 1 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0072 | 0.2592 | 1 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0186 | 1 | 1 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0186 | 1 | 1 |
Mycobacterium ulcerans | malate dehydrogenase | 0.0072 | 0.2592 | 0.5 |
Plasmodium vivax | malate dehydrogenase, putative | 0.0186 | 1 | 1 |
Echinococcus multilocularis | L lactate dehydrogenase | 0.0114 | 0.5289 | 0.3641 |
Schistosoma mansoni | malate dehydrogenase | 0.0186 | 1 | 1 |
Toxoplasma gondii | lactate dehydrogenase LDH2 | 0.0186 | 1 | 0.5 |
Brugia malayi | Probable malate dehydrogenase, mitochondrial precursor | 0.0072 | 0.2592 | 0.2592 |
Trypanosoma cruzi | mitochondrial malate dehydrogenase, putative | 0.0072 | 0.2592 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.