Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0362 | 0.4415 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0156 | 0.1727 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0362 | 0.4415 | 0.2361 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0362 | 0.4415 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0225 | 0.2627 | 0.5951 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0156 | 0.1727 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0362 | 0.4415 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0362 | 0.4415 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0362 | 0.4415 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0362 | 0.4415 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0362 | 0.4415 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0362 | 0.4415 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0362 | 0.4415 | 0.2361 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0362 | 0.4415 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 0.2627 | 0.5951 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0362 | 0.4415 | 0.2361 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0293 | 0.0664 |
Brugia malayi | carbohydrate phosphorylase | 0.0362 | 0.4415 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.2689 | 0.6091 |
Schistosoma mansoni | glycogen phosphorylase | 0.0362 | 0.4415 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0156 | 0.1727 | 0.3478 |
Brugia malayi | hypothetical protein | 0.023 | 0.2689 | 0.6091 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0362 | 0.4415 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0362 | 0.4415 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0362 | 0.4415 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.