Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.1847 | 0.5 |
Trypanosoma brucei | unspecified product | 0.002 | 0.1847 | 0.1904 |
Leishmania major | DNA polymerase eta, putative | 0.0033 | 0.5597 | 0.4775 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.1847 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.1847 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.9701 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0033 | 0.5597 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.9701 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.9701 | 0.9633 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1847 | 0.1904 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.1847 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1847 | 0.1904 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.1847 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.9701 | 0.9633 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.9701 | 0.9633 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.1847 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.9701 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1847 | 0.1904 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.9701 | 0.9633 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0033 | 0.5597 | 0.4775 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.9701 | 0.9633 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1847 | 0.1904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.