Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha-glucosidase | 0.0158 | 0.821 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0048 | 0.0495 | 0.1012 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0756 | 0.0756 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.011 | 0.4888 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0048 | 0.0495 | 0.1012 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0756 | 0.0756 |
Echinococcus granulosus | glycogen phosphorylase | 0.011 | 0.4888 | 0.4888 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0048 | 0.0495 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0048 | 0.0495 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.011 | 0.4888 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.011 | 0.4888 | 0.5954 |
Giardia lamblia | Glycogen phosphorylase | 0.011 | 0.4888 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.011 | 0.4888 | 0.4888 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.011 | 0.4888 | 0.4888 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0041 | 0 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.011 | 0.4888 | 0.4888 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0756 | 0.0756 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.011 | 0.4888 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.011 | 0.4888 | 0.4888 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0048 | 0.0495 | 0.1012 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0041 | 0 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0756 | 0.0756 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.011 | 0.4888 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0041 | 0 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0158 | 0.821 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0183 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.011 | 0.4888 | 0.4888 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0183 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.011 | 0.4888 | 0.4888 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0756 | 0.0756 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.011 | 0.4888 | 0.4888 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0183 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.011 | 0.4888 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0183 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0048 | 0.0495 | 0.0603 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Schistosoma mansoni | glycogen phosphorylase | 0.011 | 0.4888 | 0.5954 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0756 | 0.0756 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.011 | 0.4888 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.