Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0022 | 0.1183 | 0.1183 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0075 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0075 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Loa Loa (eye worm) | fibroinase | 0.0022 | 0.1183 | 0.1183 |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0075 | 1 | 1 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0075 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0022 | 0.1183 | 0.1183 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0075 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0022 | 0.1183 | 0.1183 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0075 | 1 | 0.5 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0075 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0075 | 1 | 1 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 1 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0075 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | Cathepsin L homolog | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0075 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Echinococcus granulosus | cathepsin l1 | 0.0022 | 0.1183 | 0.1183 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0075 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0075 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0022 | 0.1183 | 0.1183 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0075 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.1183 | 0.1183 |
Plasmodium vivax | RNA helicase-1, putative | 0.0075 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0022 | 0.1183 | 0.1183 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0075 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0022 | 0.1183 | 0.1183 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0075 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.1183 | 0.1183 |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0075 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0075 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0.1183 | 0.1183 | |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0075 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.1183 | 0.1183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0022 | 0.1183 | 0.1183 |
Entamoeba histolytica | cysteine protease, putative | 0.0022 | 0.1183 | 0.1183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.