Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | transporter, cation channel family protein | 0.0058 | 0 | 0.5 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0058 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Brugia malayi | olfactory channel protein osm-9 | 0.0058 | 0.0000089447 | 0.0000089447 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0058 | 0 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0091 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0091 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0091 | 1 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0058 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0058 | 0.0000089447 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0000089447 | 0.0000089447 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0058 | 0 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0091 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0000089447 | 0.0000089447 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0091 | 1 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Onchocerca volvulus | 0.0058 | 0 | 0.5 | |
Leishmania major | cytochrome p450-like protein | 0.0091 | 1 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0058 | 0.0000089447 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0091 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0058 | 0 | 0.5 |
Trypanosoma brucei | cytochrome P450, putative | 0.0091 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0091 | 1 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0058 | 0 | 0.5 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0058 | 0 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0058 | 0.0000089447 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0000089447 | 0.0000089447 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.