Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.019 | 0.4233 | 0.4576 | |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0143 | 0.2461 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Brugia malayi | C1-like domain containing protein | 0.0188 | 0.4157 | 0.5436 |
Brugia malayi | Protein kinase c protein 2 | 0.0231 | 0.5757 | 0.7529 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.4233 | 0.4233 |
Echinococcus granulosus | protein kinase C gamma type | 0.0236 | 0.5927 | 0.5977 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1637 | 0.1637 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0302 | 0.8372 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0282 | 0.7647 | 0.8807 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.4082 | 0.4082 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0302 | 0.8372 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0156 | 0.296 | 0.1096 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0302 | 0.8372 | 1 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0188 | 0.4157 | 0.5436 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0188 | 0.4157 | 0.4157 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0165 | 0.3312 | 0.3312 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0209 | 0.4925 | 0.4328 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.7311 | 0.7311 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.7311 | 0.7311 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0302 | 0.8372 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0122 | 0.1712 | 0.1712 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0236 | 0.5927 | 0.5977 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0282 | 0.7647 | 0.8807 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0282 | 0.7647 | 0.8807 |
Onchocerca volvulus | 0.0186 | 0.4082 | 0.431 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.296 | 0.296 |
Onchocerca volvulus | 0.0273 | 0.7311 | 1 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0139 | 0.231 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1637 | 0.1637 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0156 | 0.296 | 0.1096 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0076 | 0 | 0.5 |
Schistosoma mansoni | protein kinase C mu | 0.0188 | 0.4157 | 0.3065 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.9756 | 0.9756 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0282 | 0.7647 | 0.7647 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0156 | 0.296 | 0.1096 |
Brugia malayi | protein kinase C II. | 0.0282 | 0.7647 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.7311 | 0.7311 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.5405 | 0.5405 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.