Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.4154 | 0.1744 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4154 | 0.1744 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2919 | 0.0261 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.4154 | 0.1744 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4154 | 0.1744 |
Loa Loa (eye worm) | acetyltransferase | 0.0143 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.4154 | 0.1744 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.4154 | 0.1744 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2919 | 0.0261 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4154 | 0.1744 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.2485 | 0.5 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0143 | 1 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.2737 | 0.5 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0143 | 1 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.2737 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.4154 | 0.2031 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.2485 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4154 | 0.1744 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.4154 | 0.1744 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0139 | 0.9711 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.2737 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4154 | 0.1744 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.2737 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.4154 | 0.1744 |
Brugia malayi | RNA binding protein | 0.0062 | 0.4154 | 0.1744 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.2485 | 0.5 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.2737 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.