Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0046 | 1 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.007 | 0.0046 | 1 |
Echinococcus multilocularis | calpain A | 0.007 | 0.0046 | 1 |
Brugia malayi | calpain family protein 1 | 0.0067 | 0.0039 | 1 |
Brugia malayi | calpain family protein 1 | 0.0067 | 0.0039 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0039 | 1 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0046 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0001 | 0.0218 |
Trichomonas vaginalis | conserved hypothetical protein | 0.5142 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein | 0.5142 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.5142 | 1 | 0.5 |
Trypanosoma brucei | nucleoside 2-deoxyribosyltransferase | 0.5142 | 1 | 0.5 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0046 | 1 |
Trypanosoma cruzi | hypothetical protein | 0.5142 | 1 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0001 | 0.0256 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0001 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0039 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.5142 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.5142 | 1 | 0.5 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Echinococcus granulosus | calpain A | 0.007 | 0.0046 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0067 | 0.0039 | 0.8502 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0067 | 0.0039 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.