Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hypothetical protein | 0.4564 | 1 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0268 | 0 | 0.5 |
Trypanosoma brucei | nucleoside 2-deoxyribosyltransferase | 0.4564 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0 | 0.5 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0268 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.4564 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.4564 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0268 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.4564 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.4564 | 1 | 0.5 |
Trypanosoma cruzi | hypothetical protein | 0.4564 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.