Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.2166 | 1 | 1 |
Onchocerca volvulus | 0.0097 | 0.0327 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.2166 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0048 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0048 | 0.5 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0048 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0048 | 0.0731 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0048 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0168 | 0.0657 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0168 | 0.0657 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0048 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.0548 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0048 | 0.5 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0048 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0048 | 0.0048 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.0548 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0168 | 0.0657 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0048 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0048 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0168 | 0.0657 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0048 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2166 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0168 | 0.0657 | 0.0657 |
Toxoplasma gondii | hypothetical protein | 0.2166 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.