Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0449 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0449 | 0.0731 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0449 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0449 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 1 | 1 |
Onchocerca volvulus | 0.0094 | 0.3058 | 0.5 | |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.0248 | 1 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0449 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0449 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0449 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.5124 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0163 | 0.6143 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0163 | 0.6143 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0449 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0449 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.6143 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0449 | 0.0449 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0449 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.5124 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0248 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0163 | 0.6143 | 0.6143 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0449 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.6143 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.