Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hexokinase type 2 | 0.0241 | 0.3719 | 0.3719 |
Brugia malayi | hexokinase type II | 0.0076 | 0.0258 | 0.0559 |
Trypanosoma brucei | hexokinase | 0.0241 | 0.3719 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0258 | 0.0123 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0067 | 0.0053 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0258 | 0.0123 |
Loa Loa (eye worm) | hexokinase type II | 0.0241 | 0.3719 | 1 |
Echinococcus granulosus | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0538 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.0241 | 0.3719 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0268 | 0.4293 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.0053 | 0.0053 |
Onchocerca volvulus | 0.0241 | 0.3719 | 1 | |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0538 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0241 | 0.3719 | 1 |
Plasmodium falciparum | hexokinase | 0.0241 | 0.3719 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0538 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.0241 | 0.3719 | 0.5 |
Leishmania major | hexokinase, putative | 0.0241 | 0.3719 | 1 |
Brugia malayi | Hexokinase family protein | 0.0241 | 0.3719 | 1 |
Echinococcus granulosus | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Echinococcus multilocularis | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Trypanosoma cruzi | hexokinase, putative | 0.0241 | 0.3719 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0241 | 0.3719 | 0.5 |
Toxoplasma gondii | hexokinase | 0.0241 | 0.3719 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0074 | 0.0215 | 0.0441 |
Brugia malayi | hexokinase | 0.0241 | 0.3719 | 1 |
Brugia malayi | Hexokinase family protein | 0.0151 | 0.1828 | 0.4842 |
Trypanosoma brucei | hexokinase, putative | 0.0241 | 0.3719 | 0.5 |
Plasmodium vivax | hexokinase, putative | 0.0241 | 0.3719 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0151 | 0.1828 | 0.4604 |
Echinococcus multilocularis | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Echinococcus granulosus | hexokinase type 2 | 0.0241 | 0.3719 | 0.3719 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2106 | 0.5396 |
Schistosoma mansoni | hexokinase | 0.0241 | 0.3719 | 1 |
Treponema pallidum | hexokinase (hxk) | 0.0241 | 0.3719 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0241 | 0.3719 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Echinococcus granulosus | hexokinase | 0.0241 | 0.3719 | 0.3719 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.0053 | 0.0053 |
Leishmania major | hexokinase, putative | 0.0241 | 0.3719 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0241 | 0.3719 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.0053 | 0.5 |
Onchocerca volvulus | 0.0241 | 0.3719 | 1 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.0053 | 0.5 |
Onchocerca volvulus | 0.0241 | 0.3719 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.