Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AUR protein kinase | 0.0115 | 0 | 0.5 |
Echinococcus granulosus | aurora kinase A | 0.0115 | 0 | 0.5 |
Leishmania major | protein kinase, putative | 0.0115 | 0 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0115 | 0 | 0.5 |
Echinococcus multilocularis | aurora kinase A | 0.0115 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.234 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | protein kinase , putative | 0.0115 | 0 | 0.5 |
Mycobacterium ulcerans | bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | 0.234 | 1 | 1 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0115 | 0 | 0.5 |
Giardia lamblia | Aurora kinase | 0.0115 | 0 | 0.5 |
Trypanosoma brucei | aurora B kinase | 0.0115 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.234 | 1 | 0.5 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0115 | 0 | 0.5 |
Toxoplasma gondii | eukaryotic initiation factor-2B, gamma subunit, putative | 0.0429 | 0.1411 | 1 |
Treponema pallidum | licC protein (licC) | 0.0429 | 0.1411 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0115 | 0 | 0.5 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0115 | 0 | 0.5 |
Brugia malayi | serine/threonine kinase 12 | 0.0115 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0115 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0115 | 0 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0115 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0115 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0115 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0115 | 0 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0115 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0115 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.