Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Plasmodium falciparum | plasmepsin I | 0.0057 | 0.1835 | 1 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0057 | 0.1835 | 0.133 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.004 | 0.0582 | 0.0582 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0057 | 0.1835 | 0.1835 |
Onchocerca volvulus | Cathepsin F homolog | 0.0057 | 0.1828 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0057 | 0.1828 | 0.1828 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.004 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0582 | 0.2606 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1828 | 0.1323 |
Echinococcus granulosus | cathepsin l1 | 0.004 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0057 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0582 | 0.2606 |
Onchocerca volvulus | Cathepsin L homolog | 0.0057 | 0.1828 | 1 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0057 | 0.1835 | 0.8219 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0057 | 0.1828 | 0.9963 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0062 | 0.2232 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0057 | 0.1828 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Plasmodium vivax | vivapain-2 | 0.0057 | 0.1828 | 0.9963 |
Loa Loa (eye worm) | fibroinase | 0.0057 | 0.1828 | 0.1323 |
Plasmodium falciparum | plasmepsin VI | 0.0057 | 0.1835 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0057 | 0.1835 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0057 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0062 | 0.2232 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0057 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0062 | 0.2232 | 0.5 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0057 | 0.1835 | 0.1835 |
Echinococcus granulosus | cathepsin b | 0.0169 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Echinococcus granulosus | cathepsin b | 0.0169 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0062 | 0.2232 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.004 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0057 | 0.1828 | 0.1828 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0057 | 0.1828 | 0.1828 |
Entamoeba histolytica | cysteine protease, putative | 0.0057 | 0.1828 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Toxoplasma gondii | cathepsin B | 0.0062 | 0.2232 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.004 | 0.0582 | 0.3182 |
Plasmodium falciparum | plasmepsin II | 0.0057 | 0.1835 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.004 | 0.0582 | 0.0582 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0057 | 0.1828 | 0.1828 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.2232 | 0.2232 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0057 | 0.1828 | 0.1828 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0057 | 0.1828 | 0.9963 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1835 | 0.133 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0057 | 0.1828 | 1 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0167 | 0.987 | 0.987 |
Plasmodium falciparum | plasmepsin IV | 0.0057 | 0.1835 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0062 | 0.2232 | 0.5 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0057 | 0.1835 | 0.0169 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | cysteine protease | 0.0057 | 0.1828 | 0.1323 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | cathepsin B | 0.0062 | 0.2232 | 0.1752 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0582 | 0.0582 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0057 | 0.1828 | 0.9963 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0167 | 0.987 | 0.987 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0582 | 0.0582 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Plasmodium vivax | vivapain-2 | 0.0057 | 0.1828 | 0.9963 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0057 | 0.1835 | 0.1835 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0057 | 0.1828 | 0.1828 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0169 | 1 | 1 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0057 | 0.1835 | 0.0169 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Giardia lamblia | Cathepsin B precursor | 0.0062 | 0.2232 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Echinococcus granulosus | cathepsin l1 | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0057 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0057 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0057 | 0.1828 | 0.8189 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0057 | 0.1828 | 0.1828 |
Onchocerca volvulus | 0.0057 | 0.1828 | 1 | |
Plasmodium vivax | plasmepsin IV, putative | 0.0057 | 0.1835 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0057 | 0.1828 | 0.1323 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0057 | 0.1828 | 0.1828 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0057 | 0.1828 | 0.1323 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0062 | 0.2232 | 0.2232 |
Echinococcus multilocularis | cysteine protease | 0.0057 | 0.1828 | 0.1828 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.