Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AUR protein kinase | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0058 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | protein kinase , putative | 0.0058 | 0 | 0.5 |
Echinococcus granulosus | aurora kinase A | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0058 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.1733 | 1 | 0.5 |
Mycobacterium ulcerans | bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | 0.1733 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0058 | 0 | 0.5 |
Brugia malayi | serine/threonine kinase 12 | 0.0058 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0058 | 0 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0058 | 0 | 0.5 |
Echinococcus multilocularis | aurora kinase A | 0.0058 | 0 | 0.5 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0058 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.1733 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0058 | 0 | 0.5 |
Trypanosoma brucei | aurora B kinase | 0.0058 | 0 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0058 | 0 | 0.5 |
Treponema pallidum | licC protein (licC) | 0.0318 | 0.1553 | 0.5 |
Giardia lamblia | Aurora kinase | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0058 | 0 | 0.5 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0058 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0058 | 0 | 0.5 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0058 | 0 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0058 | 0 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0058 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0058 | 0 | 0.5 |
Toxoplasma gondii | eukaryotic initiation factor-2B, gamma subunit, putative | 0.0318 | 0.1553 | 1 |
Leishmania major | protein kinase, putative | 0.0058 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.