Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0276 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0276 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0276 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.1505 | 0.375 |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.0294 | 1 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0276 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0936 | 0.2332 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.0294 | 1 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0276 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.1505 | 0.375 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0276 | 0.0687 |
Treponema pallidum | hypothetical protein | 0.0294 | 1 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0276 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0276 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1505 | 0.375 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0276 | 0.2944 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0276 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0276 | 0.0687 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0276 | 0.2944 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0936 | 0.2332 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.1505 | 0.375 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.4013 | 1 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.0294 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0936 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0276 | 0.2944 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0276 | 0.2944 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.4013 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.4013 | 1 |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.0294 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.