Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | rab6-interacting | 0.009 | 0.2498 | 0.2498 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.009 | 0.2498 | 0.2498 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.009 | 0.2498 | 0.2498 |
Schistosoma mansoni | polycystin 1-related | 0.009 | 0.2498 | 0.2498 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.009 | 0.2498 | 0.2498 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | RUN | 0.009 | 0.2498 | 0.2498 |
Brugia malayi | Doublecortin family protein | 0.009 | 0.2498 | 0.624 |
Brugia malayi | hypothetical protein | 0.009 | 0.2498 | 0.624 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2498 | 0.7312 |
Schistosoma mansoni | rab6-interacting | 0.009 | 0.2498 | 0.2498 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3416 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2333 | 0.683 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.009 | 0.2498 | 0.2498 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0099 | 0.292 | 0.8549 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0251 | 1 | 1 |
Onchocerca volvulus | 0.0122 | 0.4003 | 1 | |
Echinococcus multilocularis | aminopeptidase N | 0.0122 | 0.4003 | 0.4003 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2498 | 0.7312 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | loxhd1 | 0.009 | 0.2498 | 0.2498 |
Onchocerca volvulus | 0.009 | 0.2498 | 0.624 | |
Loa Loa (eye worm) | doublecortin family protein | 0.009 | 0.2498 | 0.7312 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.009 | 0.2498 | 0.2498 |
Brugia malayi | hypothetical protein | 0.009 | 0.2498 | 0.624 |
Echinococcus granulosus | RUN | 0.009 | 0.2498 | 0.2498 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0036 | 0 | 0.5 |
Onchocerca volvulus | 0.009 | 0.2498 | 0.624 | |
Echinococcus granulosus | aminopeptidase N | 0.0122 | 0.4003 | 0.4003 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0036 | 0 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0122 | 0.4003 | 1 |
Entamoeba histolytica | aminopeptidase, putative | 0.0036 | 0 | 0.5 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.009 | 0.2498 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0036 | 0 | 0.5 |
Plasmodium falciparum | LCCL domain-containing protein | 0.009 | 0.2498 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.2498 | 0.2498 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.009 | 0.2498 | 0.2498 |
Schistosoma mansoni | lipoxygenase | 0.009 | 0.2498 | 0.2498 |
Schistosoma mansoni | lipoxygenase | 0.0251 | 1 | 1 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0036 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.