Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0138 | 1 | 0.5 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0138 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0086 | 0.4443 | 0.4443 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0086 | 0.4443 | 0.4443 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0138 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0138 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0138 | 1 | 0.5 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0138 | 1 | 0.5 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0138 | 1 | 0.5 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0138 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0086 | 0.4443 | 0.4443 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0138 | 1 | 0.5 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0138 | 1 | 0.5 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0138 | 1 | 0.5 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0138 | 1 | 0.5 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0138 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0086 | 0.4443 | 0.4443 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0138 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0138 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0138 | 1 | 0.5 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0138 | 1 | 0.5 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0138 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.