Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | hypothetical protein | 0.2523 | 0.5051 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.4884 | 1 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.4884 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.4884 | 1 | 0.5 |
Schistosoma mansoni | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.1064 | 0.1992 | 0.1992 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.4884 | 1 | 0.5 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.3167 | 0.64 | 0.64 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0666 | 0.1157 | 0.1157 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Brugia malayi | Animal haem peroxidase family protein | 0.0666 | 0.1157 | 0.1157 |
Schistosoma mansoni | hypothetical protein | 0.2523 | 0.5051 | 0.5051 |
Echinococcus granulosus | carbonic anhydrase II | 0.4884 | 1 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.2523 | 0.5051 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.3167 | 0.64 | 0.64 |
Echinococcus granulosus | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | alpha-glucosidase | 0.1064 | 0.1992 | 0.1992 |
Echinococcus multilocularis | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Brugia malayi | Peroxidasin | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.4884 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Echinococcus granulosus | peroxidasin | 0.0666 | 0.1157 | 0.1157 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1064 | 0.1992 | 0.1992 |
Brugia malayi | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.2523 | 0.5051 | 0.5051 |
Echinococcus granulosus | bile acid beta glucosidase | 0.3167 | 0.64 | 0.64 |
Leishmania major | carbonic anhydrase-like protein | 0.4884 | 1 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0666 | 0.1157 | 0.1157 |
Echinococcus multilocularis | peroxidasin | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.3929 | 0.7998 | 0.7998 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.4884 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Brugia malayi | Ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Brugia malayi | Blistered cuticle protein 3 | 0.0666 | 0.1157 | 0.1157 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.2523 | 0.5051 | 0.5051 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.2523 | 0.5051 | 0.5051 |
Brugia malayi | Animal haem peroxidase family protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2717 | 0.5457 | 0.6808 |
Echinococcus multilocularis | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | carbonic anhydrase-related | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | alpha-glucosidase | 0.1064 | 0.1992 | 0.1992 |
Echinococcus multilocularis | carbonic anhydrase II | 0.4884 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0666 | 0.1157 | 0.1157 |
Giardia lamblia | Ceramide glucosyltransferase | 0.1645 | 0.321 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Echinococcus granulosus | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.2523 | 0.5051 | 0.5051 |
Echinococcus granulosus | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Loa Loa (eye worm) | hypothetical protein | 0.2138 | 0.4242 | 0.4242 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.3929 | 0.7998 | 0.7998 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | peroxidasin | 0.0666 | 0.1157 | 0.1157 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.2523 | 0.5051 | 0.5051 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.4884 | 1 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1064 | 0.1992 | 0.1992 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.2578 | 0.5166 | 0.6453 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.4884 | 1 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.3167 | 0.64 | 0.64 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.3629 | 0.7369 | 0.7369 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.2523 | 0.5051 | 0.5051 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1064 | 0.1992 | 0.1992 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2578 | 0.5166 | 0.6442 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.3167 | 0.64 | 0.64 |
Onchocerca volvulus | 0.0715 | 0.126 | 0.0166 | |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.2523 | 0.5051 | 0.5051 |
Schistosoma mansoni | carbonic anhydrase-related | 0.2523 | 0.5051 | 0.5051 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0666 | 0.1157 | 0.1157 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.3167 | 0.64 | 0.64 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1064 | 0.1992 | 0.1992 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Brugia malayi | Animal haem peroxidase family protein | 0.0666 | 0.1157 | 0.1157 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.3629 | 0.7369 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0666 | 0.1157 | 0.1157 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.3929 | 0.7998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Brugia malayi | Animal haem peroxidase family protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 0.1157 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.2523 | 0.5051 | 0.5051 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.2717 | 0.5457 | 0.6808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.